本片开创了哥特式恐怖片的新纪元，刻画了一个形象吓人但令人同情的魔鬼人物。本题材有将近20部重拍片、改编片、续集或其他形式的延伸作品，从音乐搞笑版到超级B片一应俱全。但只有同一导演1935年的《科学怪人的新娘》（The Bride of Frankenstein）才是经典，而且有相当一部分专家认为它的艺术成就超过第一集。
Oh, in the name of God! Now I know what it feels like to be God!复制复制成功复制失败，请手动复制
Henry Frankenstein:复制复制成功复制失败，请手动复制
The brain you stole, Fritz. Think of it. The brain of a dead man waiting to live again in a body I made with my own hands!复制复制成功复制失败，请手动复制
Dr. Henry Frankenstein:复制复制成功复制失败，请手动复制
The neck's broken. The brain is useless. We must find another brain.复制复制成功复制失败，请手动复制
Dr. Henry Frankenstein:复制复制成功复制失败，请手动复制
You're quite sure you want to come in?... Very well. 复制复制成功复制失败，请手动复制
[Locks door and pockets key] 复制复制成功复制失败，请手动复制
Dr. Henry Frankenstein:复制复制成功复制失败，请手动复制
Forgive me, but I'm forced to take unusual precautions.复制复制成功复制失败，请手动复制
Henry Frankenstein:复制复制成功复制失败，请手动复制
Dangerous? Poor old Waldman. Have you never wanted to do anything that was dangerous? Where should we be if no one tried to find out what lies beyond? Have your never wanted to look beyond the clouds and the stars, or to know what causes the trees to bud? And what changes the darkness into light? But if you talk like that, people call you crazy. Well, if I could discover just one of these things, what eternity is, for example, I wouldn't care if they did think I was crazy.复制复制成功复制失败，请手动复制
Doctor Waldman:复制复制成功复制失败，请手动复制
You have created a monster, and it will destroy you!复制复制成功复制失败，请手动复制
